Adsorption and encapsulation of melittin on covalently functionalized carbon nanotubes; a molecular dynamics simulation study

Adsorption and encapsulation of melittin on covalently functionalized carbon nanotubes; a molecular dynamics simulation study

آزاده کرد‌زاده

Anticancer peptides (ACPs) have been identified with the development of
molecular biology. The positive charge, the length of about 30 residues, and
the alpha helix and beta sheet structures are the common characteristics of
ACP . Melittin, an amphiphilic peptide with 26 amino acids, is the major
component of bee venom. Melittin is a membrane-active peptide and causes
cell death by pore formation in the cell membrane, and for this reason, it is
known as an anti-cancer peptide. The toxicity and hemolytic activity of
melittin require a drug delivery system to be considered 

   

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